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Frameworks, APIs, open-source, and the modern web stack. — 40 transmissions
The ex-a16z Bio + Health chief explains why a two-person, agent-run fund makes five bets a year — and why biology data can't be scraped off the internet.
The ggml.ai team behind llama.cpp joins Hugging Face. The runtime stays 100% open source, and the transformers-to-GGUF bridge is about to get much shorter.
Z.ai and Qwen shipped near-identical hybrid LLM architectures within a day: 3:1 linear attention, a 2048-token sparse budget, four gated residual streams each.
Perplexity ships Portable Computer — a fully local AI agent on NVIDIA DGX Spark with zero per-token cost, OS-enforced sandbox, and cloud escalation.
Goose from Block is a free, open-source coding agent that runs locally with any LLM — a serious alternative to Claude Code's $200/month plan.
Google's Sovereign Agent Mesh is a zero-config, zero-trust P2P overlay that lets AI agents share tools across networks without exposing private endpoints.
Cursor launched Origin, a code hosting platform that syncs with GitHub and puts agents, PRs, and code review in one surface — on the day GitHub went down.
DeepSeek released Harness under MIT license — an agent framework where models, tools, sessions, and even the agent loop itself are swappable plugins.
NVIDIA releases Nemotron 3 Ultra, a 550B parameter MoE model with 1M context, free on OpenRouter, built for agentic AI systems.
Needle 2 is a 45M-parameter tool-calling model in a 14MB binary that runs a full session in 28MB of RAM. No GPU, no cloud, no problem.
After 25 years, Google redesigned its iconic search box with an AI-first interface. This pivot to AI search changes the game for developers and SEO.
A reader said splintr beats gigatoken. After studying its benchmarks, the answer is nuanced: it wins on flexibility and latency, gigatoken on raw throughput.